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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
39.7
Human Site:
S231
Identified Species:
58.22
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
S231
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
S220
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
S209
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Dog
Lupus familis
XP_534586
746
86477
S209
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
S231
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Rat
Rattus norvegicus
Q9JJ31
780
90872
Q228
Y
L
Q
Q
N
G
V
Q
N
Y
M
K
Y
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
E132
C
L
D
K
S
T
E
E
P
I
V
K
V
V
E
Chicken
Gallus gallus
XP_422620
768
88957
S231
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Frog
Xenopus laevis
Q6DE95
768
88933
S231
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
S229
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
T249
F
L
S
T
N
T
V
T
E
Y
L
K
H
V
E
Honey Bee
Apis mellifera
XP_625079
767
89385
S228
F
L
A
E
N
S
A
S
V
Y
I
K
K
V
E
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
A229
W
L
S
G
D
N
D
A
C
F
Y
L
A
Q
V
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
D165
E
R
A
V
H
Y
L
D
K
S
T
E
D
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
P218
W
I
Q
E
D
S
C
P
D
Y
M
L
K
S
E
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
I217
Y
Y
N
K
A
I
D
I
E
L
L
T
P
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
26.6
100
100
100
N.A.
46.6
100
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
53.3
100
100
100
N.A.
73.3
100
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
63
0
7
0
57
7
0
0
0
0
7
7
0
% A
% Cys:
7
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
13
0
13
7
7
0
0
0
7
0
7
% D
% Glu:
7
0
0
63
0
0
7
7
13
0
0
7
0
0
82
% E
% Phe:
63
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
0
0
0
7
0
7
0
7
57
0
0
7
7
% I
% Lys:
0
0
0
13
0
0
0
0
7
0
0
75
63
0
0
% K
% Leu:
0
82
0
0
0
0
7
0
0
7
13
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
7
0
69
7
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
7
0
0
0
7
7
0
% P
% Gln:
0
0
13
7
0
0
0
7
0
0
0
0
0
7
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
0
7
63
0
57
0
7
0
0
0
7
0
% S
% Thr:
0
0
0
7
0
13
0
7
0
0
7
7
0
0
0
% T
% Val:
0
0
0
7
0
0
13
0
57
0
7
0
7
69
7
% V
% Trp:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
7
0
0
0
7
0
0
0
75
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _